The Irish wing-back put in an influential performance as he made his milestone appearance, scoring the opening goal for his side as well as setting up Diogo Jota for Wolves' second, while Willy Boly made his 100th appearance in all competitions for Wolves on Sunday.
Including Doherty's 250, the 21 players which make up the senior squad have 1,309 leqgue appearances between them in gold and black, which have been made while the club has been in the Premier League, Championship and even League One.
But how well do you know the league appearances our players have made? Take our latest Wolves Trivia quiz and let us know how you got on #WolvesTrivia.