Scott Sellars head into the game on the back of a four-game unbeaten run following two wins and two draws since the beginning of November.
Despite their run of good form, Wolves are still only 10th in the Premier League 2 table however, a win this evening could take Wolves as high as sixth.
A win over Southampton, who are eighth, would take Wolves above them as they have the same points as Wolves from the same number of games.
As last week, Morgan Gibbs-White, Kortney Hause, Connor Ronan and Sylvain Deslandes are all included in the squad for this evening's game as the squad is unchanged from last Tuesday's win at home to Bournemouth.
Squad: Burgoyne, Ruddy, Odoffin, Deslandes, Hause, Goodliffe, John, Ronan, Zyro, Goncalves, Wilson, Gibbs-White, Armstrong, Herc, Seedorf, Xavier, Ashley-Seal, Breslin.
