An inch-perfect free-kick from Barry Douglas was added to when Ivan Cavaleiro finished off a fine team move, as the hosts led 2-0 at the break.
The start of the second period belonged to Leeds however, as Ezgjan Alioski pulled them back into contention, before Ronald Vieria picked up a second yellow card for chopping down Diogo Jota.
The Portuguese attacker made Leeds pay too, running through and clipping home his first goal in six games, before Helder Costa got off the mark for the season from the penalty spot.
After another three points, take a look back at the content put out on wolves.co.uk and on social media.
Match Highlights
Watch all the goals and action from Molineux below, while the Goal Cam is available on Twitter. Wolves TV subscribers can watch the extended highlights, too.
The Reaction
Hear what Nuno and Douglas had to say after the latest Wolves victory.
The Quiz
How much were you paying attention at Molineux on Wednesday night? Put your observational skills to the test with the post-match quiz below.