Wolves host Hull City tomorrow evening - the second of two home games in quick succession.
The game is likely to have a bearing at both ends of the nPower Championship table - Hull are currently in second place, six points clear of the chasing pack and could be promoted this week if results go their way.
Meanwhile, defeat at home to Huddersfield on Saturday has put Wolves in a perilous position at the wrong end of the table - two points adrift of safety with just four games remaining.
The Tigers won the reverse fixture at the KC Stadium earlier in the season - a 2-1 victory at the beginning of November.
The home side went in front after half an hour through Sone Aluko's precise free-kick, and they doubled their advantage thanks to Jay Simpson's angled finish early in the second half.
Wolves then pulled a goal back when James Chester turned Anthony Forde's low cross past his own goalkeeper, but the visitors couldn't force an equaliser, and slipped to defeat in the middle of what turned into a nine-game winless run.
Wolves haven't beaten Hull in five matches - the two games prior to this season, the only ever top flight meetings of the clubs, both ended in draws.
Hull had been promoted from the Championship the season before Wolves, and the two sides met in the fourth game of the 2009/2010 campaign.
City took the lead after just three minutes at Molineux, when Geovanni converted Stephen Hunt's cross, but the home side levelled straight after half-time through Richard Stearman.
Later on in the campaign, honours again finished even at the KC Stadium. Hull took the lead twice, through Jan Vennegoor of Hesselink and Hunt, but an Anthony Gardner own goal and a Matt Jarvis strike ensured Wolves left with a crucial point.
Whilst Wolves achieved relatively comfortable survival that year, Hull went down alongside Burnley and Portsmouth after finishing in 19th place.
Wolves' last win over the Tigers came at Molineux in April 2007, when two goals from Jay Bothroyd and a further strike from Seyi Olofinjana gave Mick McCarthy's side a 3-1 win as they chased down a play-off position.
Wolves also won both meetings during the season prior to that - with the away victory proving particularly memorable.
A thrilling game saw McCarthy's team take the lead twice - through Jeremie Aliadiere and Kenny Miller - only to be pegged back by Leon Cort and a Rob Edwards own goal. Carl Cort - Leon's older brother - then completed the scoring and earned Wolves the win in the 89th minute.
Meetings between the sides have been relatively few and far between, although they have met thirteen times since the beginning of the 1990s - with both sides winning on four occasions.
Hunt is likely to line-up against his former club tomorrow night - the Irishman played 27 times and scored six goals during his one season with the Tigers.
In the Hull ranks are former West Bromwich Albion duo Paul McShane and Robert Koren, although ex-Wolves man Olofinjana will miss out on a return to Molineux after he was loaned out to Sheffield Wednesday last month.